Primary Biliary Cirrhosis and Primary Sjögren's Syndrome: Insights for the Stomatologist

Primary Biliary Cirrhosis and Primary Sjögren's Syndrome: Insights for the Stomatologist

Primary biliary cirrhosis (PBC) is a chronic progressive autoimmune disease characterized by portal inflammation and immune-mediated destruction of the intrahepatic bile ducts. Primary Sjögren's syndrome is an autoimmune disease characterized by lymphocytic infiltration of exocrine glands, mainly the lachrymal and salivary glands, in the absence of other definitively diagnosed rheumatologic dis...

Primary biliary cirrhosis and CREST syndrome.

of the skin folds of her face and a lack of ability to open her mouth. Her limbs showed sclerodactyly and isolated telangiectases (Fig. 1a). She had positive anticentromere antibody. She was evaluated because of dysphagia with solids, pyrosis and regurgitation. The esophageal manometry showed a hypotensive lower esophageal sphincter and peristaltic waves of low amplitude in the body of the esop...

Goodpasture's syndrome associated with primary biliary cirrhosis.

A 73-year-old woman who had a history of primary biliary cirrhosis developed rapidly progressive glomerulonephritis and pulmonary-renal syndrome. She was found to have anti-mitochondrial antibody (AMA) and myeloperoxidase (MPO) anti-neutrophil cytoplasmic antibody (ANCA). She also had weak anti-glomerular basement membrane (GBM) antibody. She was treated with methylprednisolone pulse therapy, b...

Primary sclerosing cholangitis and primary biliary cirrhosis.

Preview Although primary sclerosing cholangitis occurs most often in middle-aged or younger men and primary biliary cirrhosis in middle-aged or older women, the diseases have some traits in common-unfortunate ones. In both diseases, the cause is unknown, and liver transplantation is the only known effective therapy for advanced cases. Dr Fennerty discusses trials of medical treatments used in a...

Asymptomatic primary biliary cirrhosis.